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지적재산 사항

지적재산 사항
국내외 구분 해외 지적재산 형태 특허
출원번호 US  12/605672 등록번호 8030466
출원번호 EU  09173977.1 등록번호 2305835
별명(고안)의 명칭 3′-o-fluorescently modified nucleotides and uses thereof
별명(고안)의 명칭(영문)
지적재산 분야 기타
이미지파일[C]
첨부파일
특허평가 등급   특허평가 점수  
기술가치평가 금액  

사업화 정보

지적재산 사항
지적재산 개요 및 요약 The present invention relates to a DNA sequencing method using a nucleoside triphosphate with a fluorescent blocking group on its 32-OH end as a reversible terminator. Further, the present invention relates to sequencing-by-synthesis method using the mono-modified reversible terminator (MRT), the novel nucleotide monomer having a reversible fluorescent blocking group removable chemically or enzymatically at its 32-OH end. The sequencing method of the present invention facilitates sequencing of bases inserted by terminating extension of a nucleotide chain by the nucleotide monomer and then detecting fluorescence signal from 32-OH end. At this time, after analyzing the fluorescence signal, the blocking group conjugated to the 32-OH end can be effectively removed, indicating that a free 32-OH functional group can be successfully restored, so that the next monomer insertion is possible, making continuous sequencing possible.
지적재산 거래형태 권리양도 ( 전체 )
10,000,000원 ~ 10,000,000원
지적재산 단계 아이디어 단계

#Nucleotide, #Quinching, #Expansion, #Detect, #a fluorescent signal, #a monomer, #Restore, #Removal